Hey to all my Biochemians,
The post is just to acknowledge the mastermind behind the idea of creating a blog this semester as an assignment for a Introductory to Biochemistry course.
His name is Mr. Jason Matthew, lecturer at the Univeristy of the West Indies, St. Augustine.
I must say this man is truly AWESOME, his approach in teaching skills is out of this world, from producing podcasts, in class quizes as well as online, assignments straight down to this blog has allowed me to understand this course.
I must say he really deserve a reward and for that I would like to say if I, Shanice Sade Charles is awarded an A+ in this final exam , I would get this Hokage what he likes best a MOCHA CHILLER…..
So you guys stay tuned to find out if this came true…
The picture above is a jig saw puzzle of the man himself…….
Thanks Sir for allowing me the oppurtunity to learn Biochemistry at it’s best!!!
For my international blog followers, please suscribe to his Youtube link that is posted at the bottom to get all his videos on Biochemistry.
As I go, I leave this quote:
A good teacher can inspire hope, ignite the imagination, and instill a love of learning: Brad Henry
“Sildenafil in the treatment of erectile dysfunction: an overview of the clinical evidence”. 2006. Accessed March 30,2013.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699643/
With increasing aging of men and their never ending sexual desire to be sexually intimate with their love one, a major sexual concern for them is erectile dysfunction which is known as a chronic disease.
Well my friends the answer to this major concern is the use of Sildenafil or as we all know it VIAGRA.
Viagra is an inhibitor of phosphodiesterase type 5 (PDE 5i). This inhibitor causes an increase in intracellular concentration of cGMP in the smooth muscles which is found on the lining of the blood vessels that supplies the corpus cavernosum of the penis. Thus patients that use this drug are advised to administer it one hour before sexual intercourse daily which allows sexual intercourse to be maintained from 30 minutes to four to five hours from taking it.
The use of Viagra tends to improve men’s self-esteem, confidence as well as sexual relationship satisfaction which is reported after treatment of erectile dysfunction when Viagra is taken.
Viagra changes the structure and function of the penis by hormonal changes. It has been recorded that men over 5 years have a higher plasma concentration than men ages 18-45. PDE5i has been thought to benefit patients that have premature ejaculation which is due to inhibition of contractile responses in the prostate, vas-deferens ,seminal vesicles and urethra.
Hope you learn’t a little something……*wink wink *
The above video is a bit long but it contains all the vital information needed for this topic in biochemistry…..
Hope you learn something new…..
It’s me again……This week we spent some time looking into the Kreb’s cycle or the TCA cycle which we are familiar with its where under aerobic conditions the pyruvate is converted to acetyl CoA.
The following is a nice depiction of this said cycle:
Next we look at the elctron transport chain, here is a diagram of how it works:
It’s two more weeks for the end of this semester and I must really say that I am impressed with my achievement of being able to write a blog, it was a challenge at first but I succeeded…..I hope u guys learnt somethings on the basic introductory course in biochemistry next week I would give my final farewell as I begin to start to study for my final exams!!
Wait but I have a surprise!!!!!!!! 😮
I would continue blogging as I journey through the next two years while completing my Biochemistry major…so this is not the last of me!! So see you very very soon 🙂
Its me again, this a review of a published paper I found out about fructose hope u learn something…..
Department of Pediatrics and Philip R. Lee Institute for Health Policy Studies.2013. “Fructose: It’s “Alcohol without the Buzz.” Univeristy of Califonia, San Francisco, CA. Accessed March 30,2013. http://www.ncbi.nlm.nih.gov/pubmed/23493539
Can a diet high in fructose leads to obesity?
Well just like there is lactose intolerance, there is also fructose intolerance where there is a deficiency the enzyme fructose-1-phosphate aldolase B which can lead to a person to be unable to consume any source of fructose else they would be hypoglycemic.
The action fructose displays on the body imitates that of ethanol which is a very unessential energy source. This paper seeks to give information on how ethanol and fructose are similar and different.
Glut5 transporter is found in the liver which metabolizes fructose. While glucose which we know when in excess is converted to glycogen by insulin, fructose however is not converted to glycogen directly. Fructose is phosphorylated without insulin to fructose-1-phosphate which is catalyzed by fructokinase. Fructose 1 phosphate then enters the glycolysis pathway which is metabolized to pyruvate which produces a large volume of acetyl-CoA which enters the Krebs cycle. Fructose goes down a lipogen pathway which triples the rate of DNL.
Ethanol is not metabolized by the glycolytic pathway however it is converted to acetaldehyde by the enzyme alcohol dehydrogenase which then is metabolized by aldehyde dehydrogenase 2 to acetic acid. The acetic acid is then converted to acetyl Co A which enters the Krebs cycle. A large consumption of ethanol produces a large amount of acetyl CoA, the ethanol is then converted to FFA’s through DNL.
Fructose verses Ethanol
When taken in small amount they will not go over the hepatic mitochondrial capacity. They both drive DNL which is insulin resistant. Fructose benefits insulin secretion like alcohol in small amounts. However they are both dependent on the doses. Fructose can cause dyslipidemia, hepatic seatosis and insulin resistance similar to ethanol. Although ethanol is manufactured by fructose fermentation, the yeast in ethanol is used for glycolysis while us humans our own body perform glycolysis for metabolizing fructose. Fructose does not have the same toxic effects as ethanol however it does have a long term chronic toxic effect on your health.